Endocrine Abstracts

This case series compared the efficacy of long acting basal Insulin, Insulin Degludec compared to Insulin Glargine in adolescent paediatric patients. There were seven patients in total aged 14 to 18 years. Changes in HbA1c, BMI and reduction in nocturnal hypoglycaemic episodes were compared in all seven patients. Insulin Degludec showed a decrease in HbA1C levels, particularly in patients who had HbA1C higher than 48 mmol/mol on Insulin Glargine. There was a 2.4% decrease in H...

Introduction: Chromosome 9p trisomy is a rare chromosomal syndrome in which a portion of the 9th chromosome appears three times rather than twice in cells of the body. Most often these children present with developmental delay, craniofacial malformation and growth deficiency. We present a case of insulin dependent diabetes in a 5-year-old boy known to have a diagnosis of Chromosome 9p trisomy.Case: Born at 38+3, by normal vaginal delivery with birth weig...

Aims: To understand whether insulin treatment for type 1 diabetes mellitus (T1DM) in the paediatric population is most effective at providing diabetic control when delivered by Multiple Daily Injections (MDI) as compared to Continuous Subcutaneous Insulin Infusion (CSII).Methods: A District General Hospital’s submissions to the National Paediatric Diabetes Audit (NPDA) between 2012 and 2018 were analysed to establish if either method of insulin deli...

Objectives: The purpose of this study was to review the effectiveness of the Freestyle Libre flash glucose monitoring system at improving glycaemic control in a paediatric clinic.Methods: Data from 13 participants with type 1 diabetes for the first 3 months of use of the Freestyle Libre system either continuously or intermittently was collected using both clinic readings of glycated haemoglobin (Hba1c) and from the Libre itself using the Diasend diabetes...

Introduction: Continuous s.c. insulin infusion delivered via insulin pump has enabled patients with diabetes mellitus type 1 to improve metabolic control and lead healthier lives1. However some patients are experiencing problems with their pumps.Aim and methods: A service review was carried out to look at the incidence of pump related problems using an online questionnaire survey.Results: The response rate was 85% for th...

Introduction: The study aimed to review the service provided for children and young people with type 1 diabetes mellitus focusing on their quality of life (QoL) before and after commencing insulin pump therapy.Methods: An online survey using survey monkey was carried out. Each questionnaire had 10 questions and it was filled by either patients or their parents based on the age group.Results: Forty-two patients are currently on insu...

Diabetic ketoacidosis (DKA) is a common medical emergency in children. Altered consciousness in the form of mild disorientation or confusion can occur but frank coma is uncommon.1 We present a case of a newly diagnosed Type 1 diabetes mellitus who presented in DKA and with glasgow coma scale (GCS) of seven. She developed decorticate posturing soon after she was commenced on resuscitation fluids.Case: A previously well 15-year-old girl was rush...

Introduction: Nearly all patients with type 1 diabetes mellitus develop diabetic retinopathy (DR) within 20 years of diagnosis. It is the second largest cause of blindness in those of working age in the UK. Several risk factors have been accepted by the Royal College of Ophthalmologists, including gender, duration of diabetes, glycaemic control, blood lipid profile, blood pressure, and renal impairment.Aim: To study the epidemiology of DR and its associa...